Anti-ALDH1A1 Antibody

This rabbit polyclonal antibody from Antibodies.com targets ALDH1A1 (aldehyde dehydrogenase 1A1), a cytosolic NAD-dependent enzyme that oxidises retinaldehyde to retinoic acid and serves as a recognised marker of normal and cancer stem-like cell populations. Provided as 100 µl of a 1 mg/ml solution in PBS with 0.1% sodium azide and 50% glycerol, the unconjugated reagent works in western blot, immunohistochemistry, and immunofluorescence workflows on human, mouse, and rat specimens.

ALDH1A1 is investigated in cancer stem cell biology across breast, lung, colon, prostate, and pancreatic models, in retinoid signalling studies of embryonic and adult tissue, and in hepatic aldehyde detoxification. Researchers apply it to characterise tumour-initiating cell populations, retinoic acid-driven transcription, and xenobiotic metabolism pathways. For routine handling, keep the vial at 4°C; for long-term storage, aliquot and freeze at -20°C, limiting freeze-thaw cycles to preserve antibody titre and binding activity over time.