Anti-AKT3 Antibody

AKT3 is a serine/threonine kinase and the third member of the AKT/PKB family, sitting downstream of PI3K to relay growth factor, insulin, and GPCR cues into cellular decisions about survival, proliferation, and metabolism. Antibodies.com supplies this unconjugated rabbit polyclonal IgG reagent in a 200 µl vial format, validated for Western blot (WB) and immunohistochemistry (IHC) workflows on human, mouse, rat, and monkey samples. Investigators working in PI3K/AKT/mTOR pathway biology rely on AKT3 detection to separate isoform-specific contributions in melanoma, glioma, and breast carcinoma lysates, while IHC use enables tissue-level surveys of AKT3 distribution in cortical development, megalencephaly research, and neurological disease models. Because the antibody is polyclonal and raised in rabbit, it targets several epitopes on native AKT3, which helps tolerate minor variation between fixation and lysis protocols. Aliquot on receipt, store refrigerated for routine short-term use, avoid repeated freeze-thaw cycles, and protect from light to preserve activity. For research use only; not intended for diagnostic procedures.