Anti-AKT1 (phospho T450) Antibody

This rabbit polyclonal antibody from Antibodies.com specifically recognizes AKT1 phosphorylated at threonine 450 (T450), a regulatory autophosphorylation site located within the turn motif of the kinase domain. Raised in rabbit and purified as an IgG preparation, the unconjugated reagent is supplied at 200µl and is validated for Western Blot detection of phospho-AKT1 in human samples. The antibody targets a post-translational modification linked to AKT1 maturation, stability, and downstream signaling within the PI3K-AKT-mTOR pathway, supporting studies of insulin response, growth factor signaling, and phosphorylation-dependent regulation of AKT1 in cell lysates.