Anti-AKT1 Antibody [Assigned #A10605]

This Mouse monoclonal IgG antibody from Antibodies.com targets AKT1 (also known as Protein Kinase B alpha, PKBα), a serine/threonine kinase encoded by the AKT1 gene. The unconjugated reagent is supplied as 100 µl of liquid and is validated for Western Blot detection of the human AKT1 protein in research samples.

AKT1 is a key node in the PI3K/AKT signaling cascade, phosphorylating downstream substrates such as GSK3β, BAD, and FOXO transcription factors to regulate cell survival, proliferation, glucose metabolism, and protein synthesis. Because the pathway is frequently dysregulated in cancers, metabolic disorders, and insulin-resistance studies, the antibody is widely used in Western Blot workflows to monitor AKT1 expression levels and phosphorylation status across human cell lines and primary tissues.

Produced in mouse hosts and purified as a monoclonal IgG, the reagent provides lot-to-lot consistency for reproducible Western Blot results. Researchers studying oncogenic signaling, diabetes models, or growth-factor responses can pair the antibody with anti-phospho-AKT antibodies to dissect activation-state dynamics. Each vial is intended for research use only and should be stored according to standard antibody handling guidance to preserve immunoreactivity.