Anti-Akt1 Antibody

The Akt1 (also known as PKBα or Protein Kinase B alpha) targeting reagent from Antibodies.com is a rabbit polyclonal antibody supplied as 100 µl of unconjugated reagent. Akt1 is a serine/threonine kinase that operates within the PI3K/AKT signaling axis, regulating glucose uptake, cell growth, survival, and migration across many tissue types. Aberrant Akt1 activity is implicated in oncogenesis, metabolic disease, and immune dysregulation, which is why Akt1 is a frequent subject of cancer biology, signaling, and metabolism research.

Recommended applications include Western blot for measuring endogenous Akt1 expression and phosphorylation status in cell lysates, immunohistochemistry for visualizing Akt1 distribution in tissue sections, and ELISA for quantitative detection in experimental samples. Reactivity has been validated in human, mouse, and rat samples, supporting translational studies that move between model systems and clinical material. The antibody is supplied in a vial at 100 µl, with the unconjugated format allowing it to be paired with secondary antibodies or custom labels of the researcher's choice for flexibility across experimental designs.