Anti-AKT (P470) Antibody

This rabbit polyclonal reagent from Antibodies.com targets AKT, a serine/threonine kinase that operates as a central node in the PI3K/AKT/mTOR signaling cascade governing cell survival, proliferation, and glucose metabolism. The unconjugated antibody is supplied in a 50 µl vial at 1 mg/ml in phosphate buffered saline containing 0.05% sodium azide at approximately pH 7.2, ready for direct dilution into standard blotting and staining workflows. The P470 designation identifies the peptide epitope used for immunization. Confirmed reactivity covers human, mouse, and rat samples, supporting comparative studies of AKT expression and regulation in cultured cell lysates and fixed tissue sections. Validated applications include western blot and immunohistochemistry, providing flexibility for both protein-level quantification and spatial localization experiments. The polyclonal clonality broadens epitope coverage across the AKT1, AKT2, and AKT3 isoforms, which is useful when probing total AKT levels rather than a single isoform. Store refrigerated and aliquot to limit freeze-thaw cycles; intended for research use only and not for diagnostic or therapeutic applications.