Anti-AKT (F469) Antibody

Raised in rabbit against the AKT (also known as PKB or Protein Kinase B) serine/threonine kinase, this polyclonal antibody from Antibodies.com targets the F469 epitope region of the protein. AKT sits at the core of the PI3K/AKT/mTOR signaling cascade, where it integrates upstream growth factor cues to govern glucose metabolism, apoptosis, cell proliferation, transcription, and migration, becoming catalytically active after membrane recruitment and phosphorylation at key regulatory residues.

The unconjugated reagent is supplied as 100 µl at 1 mg/ml in phosphate buffered saline (PBS) containing 0.05% sodium azide at approximately pH 7.2, and has been validated for western blot and immunohistochemistry workflows on Human, Mouse, and Rat samples. Researchers commonly use it to probe AKT pathway activity in cell lysates and tissue sections, and the 0.05% sodium azide preservative allows convenient bench-top handling without immediate dialysis for most short-term western blot and immunohistochemistry applications.