Anti-AKR1B1 Antibody

This rabbit polyclonal reagent from Antibodies.com targets AKR1B1 (also known as Aldose Reductase, ALDR1, or Aldo-keto reductase family 1 member B1), an enzyme implicated in diabetic complications, osmotic stress responses, and polyol pathway metabolism. The antibody is supplied as an unconjugated IgG preparation at 1 mg/ml, presented in a 50 µl vial, and is validated for Western blotting as well as immunohistochemistry and immunocytochemistry/immunofluorescence applications. Raised in rabbit, the polyclonal antibody is reactive with human, mouse, and rat samples, making it a versatile reagent for cross-species studies of aldose reductase expression in cell lysates and tissue sections. For best results and long-term stability, the manufacturer recommends storing the vial at −20 °C for continuous use, with aliquots recommended to limit repeated freeze-thaw cycles. Researchers in endocrinology, ophthalmology, and metabolic disease research will find this reagent particularly useful for probing AKR1B1 protein levels under hyperglycaemic or oxidative stress conditions, and the unconjugated format allows flexible pairing with secondary antibodies or custom labelling protocols depending on experimental design.