Anti-AKAP5 Antibody

A polyclonal reagent from Antibodies.com raised in rabbit provides specific detection of the AKAP5 scaffolding protein, also referenced in the literature as AKAP79 and AKAP150. AKAP5 anchors protein kinase A, protein kinase C, and calcineurin at defined subcellular sites, making this reagent useful for studying compartmentalized cAMP-dependent signaling in neurons and cardiac tissue, including the regulation of L-type calcium channels and postsynaptic plasticity.

Supplied as 50 µl of unconjugated IgG in a single vial, the antibody has been validated for Western blot and Immunohistochemistry workflows and cross-reacts with Human, Mouse, and Rat samples. Researchers investigating synaptic function, neuronal signaling, or cardiac excitation-contraction coupling can use it to localize AKAP5 in fixed tissue sections and to confirm expression by Western blot. The polyclonal format offers recognition of multiple epitopes on the target, supporting consistent detection across different species and sample preparations.

For best results, refrigerate the vial upon arrival, protect it from light, and prepare working aliquots to limit freeze-thaw cycles of the stock.