Anti-AKAP5 Antibody

Raised in rabbit against A-kinase anchoring protein 5, this unconjugated polyclonal IgG reagent from Antibodies.com is supplied at 1.0 mg/mL in a 200 µL vial and detects endogenous levels of total AKAP5 protein across human, mouse, and rat samples. AKAP5 acts as a scaffold that concentrates protein kinase A and other signaling enzymes at defined membrane microdomains, so researchers deploy this reagent in Western blot workflows to resolve the characteristic 47 and 79 kDa bands and in immunohistochemistry to map compartmentalized PKA signaling in neurons, cardiac myocytes, and other excitable tissues. The antibody supports studies of AMPA receptor trafficking at excitatory synapses, GPCR regulation, long-term potentiation, learning and memory models, and arrhythmia susceptibility, and is compatible with downstream immunolabeling pipelines that demand consistent lot-to-lot reactivity. Aliquot upon arrival and store at -20 °C, avoiding repeated freeze-thaw cycles to preserve affinity for the AKAP79/150 scaffold.