Anti-AKAP12 Antibody

This rabbit polyclonal reagent from Antibodies.com targets AKAP12 (A-kinase anchor protein 12), a large multivalent scaffolding polypeptide also known as Gravin and SSeCKS that organizes protein kinase A (PKA) and other signaling enzymes at the cytoskeleton and plasma membrane. The unconjugated antibody is raised in rabbit and validated for Western blot and immunohistochemistry on human samples, making it a practical tool for studies of AKAP12 expression in tumor suppressor pathways, cytoskeletal remodeling assays, and signaling compartmentalization research. The product is supplied as 100 µl of liquid in a single vial; for best stability, the reagent should be aliquoted, stored frozen, and protected from repeated freeze-thaw cycles. Because AKAP12 is frequently downregulated or relocalized in carcinomas, this polyclonal antibody supports immunohistochemistry workflows that explore loss of expression in prostate, gastric, and breast tissue sections, as well as Western blot experiments comparing matched tumor and normal lysates.