Anti-AK4 Antibody - Identical to Abcam (ab196792)

This rabbit polyclonal primary antibody reagent from Antibodies.com targets adenylate kinase 4 (AK4), a mitochondrial matrix enzyme also designated AK3L1 or GTP:AMP phosphotransferase AK4. The antibody is supplied unconjugated as an affinity-purified IgG liquid aliquot in a 100 µl vial and is raised against a recombinant immunogen spanning amino acids 1–219 of the human AK3L1/AK4 sequence. Validated for western blot, immunohistochemistry, immunocytochemistry/immunofluorescence, and immunoprecipitation workflows, the reagent cross-reacts with human, mouse, and rat samples, supporting comparative studies in rodent hypoxia and human tumor tissue. Because the IgG is supplied without a fluorophore or enzyme conjugate, it can be paired with a user-selected secondary antibody for chromogenic, fluorescent, or chemiluminescent detection. Storage is at -20°C, with freeze-thaw cycles avoided to preserve lot activity. AK4 sustains mitochondrial adenine nucleotide balance and has been linked to stress adaptation and tumor metabolic reprogramming, making this antibody a useful reagent for research in cancer cell biology, mitochondrial function, and hypoxic signaling. For research use only.