Anti-AICDA Antibody

The AICDA gene encodes activation-induced cytidine deaminase (AID), a member of the APOBEC family of cytidine deaminases that is essential for immunoglobulin gene diversification in activated B lymphocytes. This rabbit polyclonal antibody from Antibodies.com recognizes endogenous AID from human, mouse, and rat samples and is validated for Western blot detection of the target protein in cell and tissue lysates. The reagent is supplied as a 100 µl volume at 1 mg/ml in phosphate buffered saline (approx. pH 7.2) containing 15 mM sodium azide as a preservative, and is unconjugated for flexible pairing with custom secondary detection chemistries. The polyclonal format provides multi-epitope recognition, supporting immunoblot studies of full-length AID expression in germinal centre B cells, lymphoma cell lines, and transfected systems used to dissect class switch recombination and somatic hypermutation. For best stability, store aliquots at -20°C and limit freeze-thaw cycles.