Anti-AhR (K32) Antibody

The Aryl Hydrocarbon Receptor (AhR) is a ligand-activated transcription factor belonging to the bHLH/PAS family, widely studied in toxicology, immunology, and cancer biology. This rabbit polyclonal antibody, supplied by Antibodies.com, was raised against the K32 region of human AhR and supports detection of endogenous receptor levels in research samples.

Validated applications include Western blot for resolving the full-length receptor and immunohistochemistry for visualizing AhR distribution in tissue sections. The reagent shows reactivity with human, mouse, and rat samples, supporting comparative xenobiotic signaling studies and translational workflows across common laboratory models.

Format details: supplied at approximately 1 mg/ml in phosphate buffered saline with 15 mM sodium azide at pH ~7.2, presented unconjugated to allow flexible pairing with secondary detection reagents. Vial size is 100 µl, suitable for numerous blotting and staining experiments when titrated appropriately.

Storage handling: contains sodium azide as a preservative; aliquot upon first use to limit freeze-thaw cycles, store refrigerated, and protect from light to preserve binding activity. For longer-term storage, freeze working aliquots.

Researchers apply this reagent to investigate dioxin (TCDD)-mediated signaling, cytochrome P450 induction, immune cell differentiation, and tumor microenvironment interactions where AhR activity has documented biological roles. Host species: Rabbit. Clonality: Polyclonal. Conjugate: Unconjugated. Target: AhR.