Anti-AGR2 Antibody

AGR2 (Anterior Gradient 2, also called hAG-2 or HMP56) is a 175-amino-acid endoplasmic reticulum-resident protein disulfide isomerase implicated in mucin production, ER stress response, and tumor progression. This affinity-purified rabbit polyclonal reagent from Antibodies.com is supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, shipped as a 100 µl vial ready for direct dilution into standard western blot and immunohistochemistry buffers. Validated for WB and IHC across human, mouse, and rat samples, it supports studies of AGR2 overexpression in breast, pancreatic, ovarian, and colorectal carcinoma, where AGR2 has been proposed as both a diagnostic marker and a candidate therapeutic target. The polyclonal format provides broader epitope coverage than monoclonal alternatives, useful when probing AGR2 dimerization, post-translational modification, or secreted cleavage fragments. Aliquot and store frozen at -20°C for long-term stability and limit freeze-thaw cycles to preserve binding activity. For research use only.