Anti-AGAP2 Antibody

Generated in rabbit as a polyclonal preparation, this unconjugated reagent binds AGAP2, a GTPase-activating protein that participates in phosphoinositide 3-kinase signaling, cytoskeletal remodeling, and receptor tyrosine kinase-driven survival pathways. The antibody is validated for Western blot (WB) and immunohistochemistry (IHC) workflows on human samples, supporting studies in oncology, neurobiology, and signal transduction research.

AGAP2, also referred to in the literature as CENTG1 or PIKE, has been linked to proliferation and invasive behavior across multiple cancer cell models and to activity-dependent signaling in neuronal systems. Researchers use reagents such as this to track endogenous expression, confirm knockdown efficiency, and map subcellular localization in fixed tissue sections and lysate preparations.

The reagent is provided in a 100 µl volume, unconjugated for flexible secondary antibody pairing, and stored refrigerated to preserve functional activity. Researchers should consult the lot-specific data sheet supplied by Antibodies.com for recommended working dilutions, antigen retrieval conditions for IHC, and buffer composition for Western blot transfer.

Intended for research use only, this polyclonal preparation complements loss-of-function and rescue experiments where a clean detection reagent specific for the human AGAP2 isoform is required.