Anti-Advanced glycosylation end product-specific receptor Antibody

Reagents from Antibodies.com support research into the receptor for advanced glycation end products (RAGE), a pattern-recognition receptor in the immunoglobulin superfamily that drives inflammatory signaling in diabetic, cardiovascular, and neurodegenerative contexts.

This unconjugated rabbit polyclonal antibody binds the human RAGE receptor and is validated for western blot and immunohistochemistry, enabling expression profiling in tissue sections and protein-level confirmation in cell or tissue lysates.

Investigators studying diabetic nephropathy, atherosclerosis, Alzheimer's disease pathology, and tumor microenvironments localize RAGE expression across vascular endothelium, renal glomeruli, alveolar epithelium, and neuronal tissue using this reagent.

The antibody is supplied at 100 µg per vial as a polyclonal reagent raised in rabbit, with confirmed reactivity against human antigen and compatibility with standard chromogenic and chemiluminescent detection workflows.

For storage, refrigerate the vial upon arrival and aliquot to limit freeze-thaw cycles, preserving binding activity across longitudinal projects investigating AGE-RAGE axis signaling, NF-κB activation downstream of ligand engagement, and receptor isoform expression patterns in disease models.