Anti-ADSS Antibody

Produced by Antibodies.com as part of their Primary Antibodies portfolio, this affinity-purified reagent is raised in Rabbit against adenylosuccinate synthetase (ADSS) and is supplied as a polyclonal, unconjugated antiserum in a 50 µl format. The antibody is validated for Western blot (WB) and Immunofluorescence (IF) workflows, allowing detection of endogenous ADSS in both denatured and native contexts, and has been shown to react with Human, Mouse, and Rat samples, making it suitable for cross-species comparative studies in cell biology and metabolic research. ADSS, also referred to as ADSS2, AMPSase 2, IMP–aspartate ligase 2, or L-type adenylosuccinate synthetase, encodes the enzyme that catalyses the first committed step in the de novo conversion of IMP to AMP, so a reliable antibody is essential for studies of nucleotide biosynthesis, proliferation, and purine-pathway regulation. The reagent is presented unconjugated, giving users full flexibility to couple it to their preferred reporter dye, biotin, or HRP label depending on the assay. For laboratories working on cell signalling, hepatic metabolism, or tumour nucleotide metabolism where adenylosuccinate synthetase activity is being interrogated, this Antibodies.com polyclonal offers a straightforward, species-flexible option for both western blotting of the ~50 kDa ADSS protein and immunofluorescence localisation in fixed cells and tissue sections.