Anti-ADSL Antibody

This rabbit polyclonal antibody targets Adenylosuccinate lyase (ADSL), the bifunctional enzyme that catalyzes the eighth and thirteenth steps of de novo purine biosynthesis: the conversion of succinylaminoimidazole carboxamide ribotide (SAICAR) to aminoimidazole carboxamide ribotide (AICAR) and of adenylosuccinate to adenosine monophosphate (AMP). Produced by Antibodies.com as an unconjugated reagent supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol, the 100 µl format is validated for Western blot and immunohistochemistry workflows on human, mouse, and rat samples. Researchers studying purine pathway disorders, including adenylosuccinate lyase deficiency (ASLD), as well as nucleotide metabolism in rapidly dividing cells and tumor biology, rely on this polyclonal reagent for sensitive detection. Aliquot on receipt, store at -20°C, avoid repeated freeze-thaw cycles, and protect from light to preserve activity across downstream applications.