Anti-ADRBK1 Antibody

Produced in rabbit and supplied by Antibodies.com as a 100 µl aliquot of unconjugated polyclonal antisera, this Primary Antibody is raised against ADRBK1 (Adrenergic Beta Receptor Kinase 1), the G protein-coupled receptor kinase 2 (GRK2) that phosphorylates agonist-occupied beta-adrenergic receptors and drives their desensitization and internalization. The Anti-ADRBK1 Antibody is validated for Western Blot (WB) and Immunohistochemistry (IHC) workflows, and demonstrates reactivity across Human, Mouse, and Rat samples, making it useful for comparative studies of cardiac, neuronal, and other tissues where GRK2-mediated regulation of GPCR signaling is under investigation. Researchers studying adrenergic signaling, receptor desensitization, cardiac beta-adrenergic responsiveness, and downstream cAMP pathway modulation will find this reagent applicable to lysate-based and tissue-section experiments.