Anti-ADPGK Antibody

This polyclonal antibody from Antibodies.com targets ADPGK (ADP-dependent glucokinase), a nucleotide-dependent metabolic enzyme that phosphorylates glucose using ADP rather than ATP as the phosphoryl donor. ADPGK has attracted growing interest in cancer metabolism research and in studies of T-cell activation, where its contribution to glucose-6-phosphate generation links metabolic flux to immune cell function and tumor-infiltrating lymphocyte biology.

Produced in rabbit hosts and purified as an IgG immunoglobulin, the reagent is supplied as an unconjugated 50 µl vial, allowing researchers to choose their own secondary label or detection chemistry for Western blot (WB) workflows. The polyclonal format provides recognition of multiple epitopes across the ADPGK protein, which is useful when probing full-length expression alongside shorter isoforms in lysates from cultured cells and primary tissues.

Validated reactivity spans human, mouse, and rat samples, supporting comparative studies in standard cell lines and rodent disease models. For best results, store the antibody refrigerated at 4 °C for short-term use or aliquot and freeze at -20 °C for longer-term storage, limiting repeated freeze-thaw cycles to preserve binding activity. This reagent is intended for research use only and is not validated for diagnostic or clinical applications.