Anti-ADH5 Antibody

Polyclonal rabbit antibody raised against ADH5 (alcohol dehydrogenase 5, also known as class III chi-chain ADH or glutathione-dependent formaldehyde dehydrogenase), supplied by Antibodies.com as an unconjugated reagent in a 100 µl volume. ADH5 catalyzes the oxidation of formaldehyde using glutathione as a cofactor, playing a central role in cellular detoxification of this reactive metabolite and contributing to nitric oxide signaling through its S-hydroxymethylglutathione activity. This reagent has been validated for western blot, immunohistochemistry, and immunofluorescence workflows, with reactivity confirmed against human, mouse, and rat samples. Recommended uses include detection of endogenous ADH5 expression in liver and testis tissue lysates, formaldehyde-metabolism studies, and oxidative stress research in cell culture models. The antibody is provided in a vial and should be stored at -20°C; working aliquots help limit freeze-thaw cycles and preserve binding performance across multiple experiments.