Anti-ADD1 (phospho S726) Antibody

The ADD1 protein (alpha-adducin) is a cytoskeletal component that promotes assembly of the spectrin–actin membrane skeleton, and phosphorylation at serine 726 is a key regulatory event linked to PKC and RhoA signaling cascades. This rabbit polyclonal IgG antibody from Antibodies.com is raised against the phospho-S726 epitope of human ADD1 and is supplied as an unconjugated 200 µl liquid aliquot in a vial format. It is validated for western blot, immunohistochemistry, and immunofluorescence workflows and cross-reacts with mouse and rat samples in addition to human, supporting comparative studies of cytoskeletal remodeling, ion transport regulation, and hypertension-related signal transduction across standard model systems. The polyclonal format provides broader epitope coverage than a monoclonal reagent, increasing the likelihood of detecting the phosphorylated target across different lysate and tissue preparations.