Anti-ADCY4 Antibody

This rabbit polyclonal antibody targets ADCY4 (Adenylate Cyclase 4), a membrane-associated enzyme that catalyzes the conversion of ATP to cyclic AMP and participates in G protein-coupled receptor signaling pathways. The unconjugated IgG reagent from Antibodies.com is supplied as a 100 µl vial and is validated for Western Blot detection in Human and Rat sample preparations.

Adenylate cyclase isoforms each play distinct roles across tissues, and ADCY4 contributes to cAMP production that influences downstream PKA activity, CREB phosphorylation, and gene transcription. Polyclonal antibodies raised against this target recognize multiple epitopes, increasing the likelihood of detecting the native protein across varied expression levels. The reagent is provided in a ready-to-use format appropriate for standard immunoblotting workflows, with reactivity confirmed against conserved regions of the enzyme.

Researchers studying GPCR signaling, second messenger pathways, or tissue-specific cAMP regulation will find this antibody useful for probing ADCY4 expression in brain and other tissues where the enzyme is endogenously expressed. Store the vial refrigerated between experiments to preserve antibody activity over multiple uses.