Anti-ADAM28 Antibody

The ADAM28 target belongs to the ADAM (A Disintegrin And Metalloproteinase) protein family, a group of zinc-dependent enzymes that mediate ectodomain shedding, integrin binding, and protease-driven remodeling of the extracellular environment. Two naturally occurring isoforms have been described: a type I transmembrane variant (ADAM28m) and a shorter secreted form (ADAM28s), both implicated in tumor cell invasion, lymphocyte signaling, and epithelial responses in inflamed airways.

From Antibodies.com, this polyclonal reagent is raised in rabbit and supplied unconjugated at 1 mg/ml in phosphate buffered saline containing 15 mM sodium azide, adjusted to approximately pH 7.2. The 100 µl volume is formulated for Western blot detection and immunohistochemistry workflows, with reactivity confirmed against human, mouse, and rat specimens so investigators can compare ADAM28 expression in matched normal and diseased tissue samples.