Anti-ACTRT1 Antibody

The ACTRT1-targeting polyclonal reagent from Antibodies.com is a rabbit host antibody raised against Actin-Related Protein T1, a testis-enriched actin-family member involved in spermiogenesis and cytoskeletal remodeling of the spermatid. Supplied as 100 µl of unconjugated antiserum, this primary antibody supports Western blot and immunohistochemistry workflows on human samples, providing a research reagent for reproductive biology, germ cell development, and cytoskeletal protein studies.

ACTRT1, also referenced in the literature as ARPT1, localizes to the cytoplasm of round and elongating spermatids and contributes to formation of the acrosomal cap and manchette structures required for sperm head shaping. Because ACTRT1 expression is essentially restricted to the testis, this antibody offers a specific marker for examining germ cell maturation, with reactivity limited to human tissue. Researchers investigating male infertility, meiotic progression, or spermatid differentiation can apply the reagent at optimized dilutions for immunoblotting of testis lysates and for chromogenic or fluorescent IHC on fixed sections.

The polyclonal format produces recognition of multiple epitopes across the ACTRT1 sequence, which can be advantageous when probing denatured targets on membranes or fixed tissue where a single linear epitope may be masked. Store refrigerated; for long-term use, aliquot and freeze to limit freeze-thaw cycles and preserve antibody activity over time.