Anti-ACTR1A Antibody

This rabbit polyclonal antiserum targets ACTR1A (alpha-centractin), the actin-related protein of the dynactin complex that tethers cytoplasmic dynein to vesicular cargo and the mitotic spindle. Manufactured by Antibodies.com as an unconjugated reagent, the antibody is supplied as 100 µL of a 1 mg/mL stock in PBS with 0.1% sodium azide and 50% glycerol for routine handling stability. Recommended applications include Western blot detection of the ~43 kDa centractin band and immunohistochemistry on formalin-fixed tissue sections. Cross-reactivity has been validated against human, mouse, and rat samples, supporting comparative work on dynactin function in mammalian systems. For day-to-day use, store working aliquots at 4 °C; for long-term storage, freeze at -20 °C in single-use portions to limit freeze-thaw cycles. Researchers studying centrosome duplication, chromosome segregation during mitosis, and microtubule-driven vesicle trafficking will find this reagent useful for both protein-level confirmation and tissue localization experiments.