Anti-ACTL6B Antibody

Targeting ACTL6B, the actin-like 6B subunit of the neuron-specific BAF (SWI/SNF) chromatin remodeling complex, this Antibodies.com reagent supports studies of chromatin regulation in post-mitotic neurons. The rabbit polyclonal antibody is provided as an unconjugated 100 µl aliquot and is validated for Western blot (WB) and immunohistochemistry (IHC) on human samples, making it well suited to investigations of dendritic development, activity-dependent gene expression, and the chromatin remodeling events underlying long-term synaptic plasticity. The polyclonal format increases the likelihood of recognizing multiple epitopes on the BAF53b protein, which is expressed predominantly in the brain and has been linked to rare neurodevelopmental disorders. Researchers studying neuronal differentiation, chromatin remodeling complexes, or ACTL6B-related intellectual disability can use this reagent to probe expression patterns and protein levels in cultured neurons and tissue sections.