Anti-ACTL6A Antibody

This polyclonal antibody from Antibodies.com targets ACTL6A (Actin Like 6A), an actin-related subunit of the SWI/SNF (BAF) chromatin remodeling complex. ACTL6A contributes to ATP-dependent nucleosome repositioning and plays documented roles in maintaining neural progenitor identity, regulating osteoblast differentiation, and supporting pluripotency programs in embryonic stem cells.

Supplied as 100 µl of unconjugated antisera raised in rabbit, the reagent is validated across a panel of applications: Western blot for protein-level expression analysis, immunohistochemistry on formalin-fixed paraffin-embedded sections, immunofluorescence for subcellular localization, immunoprecipitation to pull down ACTL6A together with its BAF complex partners, and chromatin immunoprecipitation (ChIP) for mapping ACTL6A occupancy at specific genomic loci.

The antibody has been confirmed to react with human, mouse, and rat samples, enabling cross-species studies in cancer cell lines, neural progenitors, and developing tissues where altered ACTL6A expression has been linked to tumor progression and neurodevelopmental outcomes. Suitable for research use only, this reagent is intended for laboratory applications in epigenetics, chromatin biology, and stem cell research.