Anti-ACTL6A Antibody

ACTL6A encodes the BAF53a subunit of the SWI/SNF ATP-dependent chromatin remodeling complex, an essential component of the neural progenitor BAF (npBAF) configuration that maintains proliferating neural stem cells and is exchanged for BAF53b as progenitors exit the cell cycle and undergo neuronal differentiation. This unconjugated polyclonal IgG reagent from Antibodies.com is raised in rabbit and recognizes the endogenous protein in human, mouse, and rat samples, enabling comparative detection studies across multiple model systems. Supplied at 200 µl, the antibody is validated for Western blot and immunofluorescence workflows that probe BAF complex assembly, chromatin remodeling activity, neural stem cell maintenance, and solid tumors in which ACTL6A overexpression has been documented, including hepatocellular carcinoma and head and neck squamous cell carcinoma.