Anti-ACTL6A Antibody

This unconjugated polyclonal rabbit IgG reagent from Antibodies.com targets ACTL6A (also known as BAF53a), an actin-related subunit of the SWI/SNF ATP-dependent chromatin remodeling complex. The antibody is validated for western blot (WB) and immunofluorescence (IF) workflows and cross-reacts with human, mouse, and rat samples, supporting comparative cell biology and developmental studies. ACTL6A is a recognized marker of neural progenitor proliferation and is implicated in rhabdoid tumor biology and other oncology contexts where chromatin remodeling is disrupted, so this reagent serves epigenetics, gene regulation, and cancer research programs. Each vial contains 100 µl of polyclonal antiserum supplied for research use only. In western blot, the reagent is applied to SDS-PAGE-separated lysates to detect the ~53 kDa BAF53a band; in immunofluorescence, it is used on fixed cells to reveal nuclear staining patterns consistent with chromatin remodeling factor distribution. Aliquot upon arrival and store at -20°C, avoiding repeated freeze-thaw cycles.