Anti-Actinin-α1 / 2 / 3 / 4 Antibody

This rabbit polyclonal reagent from Antibodies.com recognizes all four members of the α-actinin family (ACTN1, ACTN2, ACTN3, and ACTN4) and has been validated for western blot, immunohistochemistry, and ELISA workflows. Each 100 µl vial of unconjugated antiserum binds the conserved actin-binding region shared by muscle and non-muscle isoforms, making it useful as a pan-cytoskeletal marker for Z-disc architecture in striated muscle, focal adhesion turnover in migrating cells, and ACTN4-driven invasion in carcinoma models. The antibody reacts with human, mouse, and rat samples and is supplied without a fluorophore or enzyme tag, so it can be paired with secondary antibodies of choice for immunofluorescence, chromogenic detection, or capture assays. Aliquot upon receipt, store refrigerated for short-term use, and freeze working stocks for long-term stability to limit freeze-thaw damage. Intended for research use only in vitro applications.