Anti-Actin-κ (T121) Antibody

This polyclonal antibody from Antibodies.com selectively recognizes the kappa actin isoform, a member of the highly conserved actin family whose expression pattern can differ from the more abundant cytoplasmic and muscle actin variants. The reagent is raised in rabbit and supplied as 100 µl at 1 mg/ml in phosphate buffered saline (PBS) with 0.05% sodium azide at approximately pH 7.2, and is unconjugated so users can pair it with their preferred secondary detection system. It is validated for western blot (WB) and immunohistochemistry (IHC), supporting both denatured protein analysis in lysates and localization studies in fixed tissue sections. The polyclonal format provides multi-epitope coverage, which is useful when distinguishing closely related actin isoforms that share extensive sequence identity. Researchers investigating cytoskeletal remodelling, comparative isoform profiling, or screens where kappa actin may act as a tissue or lineage marker often rely on such polyclonal preparations because isoform-selective monoclonal reagents can be difficult to generate. The vial should be stored refrigerated and protected from light, with the sodium azide preservative taken into account for any downstream chemistry that is azide-sensitive. This 100 µl pack size is sufficient for small- to mid-scale western blot and IHC campaigns using standard immunoglobulin working dilutions.