Anti-ACTA2 Antibody [Assigned #A11111]

Smooth muscle alpha-actin, encoded by the ACTA2 gene, is a cytoskeletal protein routinely used as a marker for smooth muscle cell differentiation and myofibroblast identification. The rabbit monoclonal reagent from Antibodies.com targets this antigen and is supplied as 50 µL of unconjugated IgG, validated for western blot, immunohistochemistry, immunocytochemistry, immunofluorescence, and flow cytometry. Cross-reactivity with Human, Mouse, and Rat samples supports translational work across vascular biology, cardiac pathology, and oncology. ACTA2 expression is commonly evaluated in studies of thoracic aortic disease, vessel wall remodeling, fibrotic tissue, and smooth muscle tumors including leiomyoma and leiomyosarcoma, making this antibody a versatile tool for both fresh-frozen and formalin-fixed paraffin-embedded specimens depending on the chosen application.