Anti-ACTA2 Antibody [Assigned #A11111]

This rabbit monoclonal antibody from Antibodies.com targets ACTA2 (alpha smooth muscle actin), a 42 kDa cytoskeletal protein widely used as a marker for smooth muscle cells, myofibroblasts, and cells undergoing epithelial-to-mesenchymal transition. The unconjugated IgG reagent is validated across multiple applications including Western blot, immunohistochemistry, immunocytochemistry, immunofluorescence, and flow cytometry, and shows reactivity with human, mouse, and rat samples.

Supplied as 100 µl in a vial, the antibody supports labeling of contractile filaments in vascular and visceral smooth muscle and tracking of myofibroblast activation in tissue sections and cultured cells. Researchers apply it to characterize fibrotic remodeling in wound healing and organ fibrosis models, to resolve smooth muscle from endothelial lineages in vascular studies, and to identify cancer-associated fibroblasts and stromal changes in tumor biopsies.

The unconjugated format allows flexible pairing with custom fluorophore or enzyme conjugates depending on the detection platform. Store refrigerated at 4°C, protect from light to preserve activity, and aliquot upon receipt to limit freeze-thaw cycles and extend shelf life for ongoing immunolabeling workflows.