Anti-ACTA1 Antibody

ACTA1 encodes alpha-skeletal muscle actin, the principal thin-filament actin isoform of adult skeletal muscle sarcomeres and a protein routinely examined in studies of congenital myopathies such as nemaline myopathy and actin myopathy. This rabbit polyclonal reagent from Antibodies.com is raised against ACTA1 and validated for western blot and immunohistochemistry workflows, with reactivity confirmed against Human, Mouse, and Rat samples. Supplied as 100 µl of unconjugated antiserum for chromogenic or fluorescent detection after secondary antibody labeling, the antibody supports characterization of muscle-specific actin expression in tissue sections and cell lysates. The polyclonal format broadens epitope coverage across the actin molecule, which is helpful when probing for disease-associated variants or post-translational modifications that may mask individual linear epitopes.