Anti-ACL6A Antibody

Raised in rabbit and supplied as an unconjugated antiserum at 100 µL per vial, this Primary Antibody from Antibodies.com targets Actin-like protein 6A (ACTL6A, also called BAF53a), a nuclear subunit of the ATP-dependent SWI/SNF (BAF) chromatin remodeling complex. Validated for Western Blot and Immunofluorescence workflows, the polyclonal reagent shows reactivity against Human, Mouse, and Rat samples, supporting cross-species expression studies. ACTL6A contributes to chromatin remodeling at promoters and enhancers, participates in DNA damage response pathways, and is widely studied in neural stem cell maintenance and tumor biology, where altered expression has been documented in hepatocellular carcinoma. The polyclonal format recognizes multiple epitopes on the target, which is useful when probing conformational or post-translationally modified forms of the protein. Researchers typically aliquot the antibody upon first use and store it at -20°C in single-use portions to limit freeze-thaw cycles, handling it as a research-use-only reagent. Immunofluorescence allows subnuclear localization studies, while Western Blot supports expression profiling across cell lines and tissue lysates at the expected ~47 kDa band.