Anti-ACKR3 Antibody

Affinity-purified rabbit polyclonal reagent from Antibodies.com raised against atypical chemokine receptor 3 (ACKR3), a seven-transmembrane G protein-coupled receptor also referred to as CXCR7 or RDC1. The unconjugated IgG antibody is supplied as a 200 µL liquid aliquot and is validated for Western blot and immunohistochemistry on human samples, supporting detection of ACKR3 in cell lysates and formalin-fixed paraffin-embedded tissue sections. ACKR3 functions as a scavenger receptor for the chemokines CXCL11 and CXCL12 and is implicated in cardiac development, neuronal migration, angiogenesis, and tumor cell survival pathways, making it a reagent of interest in oncology, vascular biology, and developmental research. The polyclonal format provides recognition of multiple epitopes across the receptor, useful when probing endogenous levels in primary cells or archival specimens where epitope masking may limit monoclonal antibody performance.