Anti-AChRα5 Antibody

Raised in rabbit against the neuronal nicotinic acetylcholine receptor alpha 5 subunit (CHRNA5), this unconjugated polyclonal antibody from Antibodies.com is supplied at 1 mg/ml in PBS with 0.1% sodium azide and 50% glycerol as a 100 µl aliquot, ready for direct labeling or use in standard immunodetection workflows. The reagent recognizes human, mouse, and rat AChRα5 and has been validated for western blot and immunohistochemistry, making it useful for studies of nicotinic signaling, addiction neurobiology, and lung-cancer susceptibility loci that map to the CHRNA5 gene cluster on chromosome 15q25. Store at 4°C for short-term use, and aliquot to limit freeze-thaw cycles; the glycerol-containing buffer preserves antibody activity across long-term storage at -20°C. Researchers investigating neuronal nAChR subunit composition, dopaminergic reward circuitry, or the contribution of α5-containing receptors to GABAergic and dopaminergic neuron firing will find this reagent a flexible tool for protein-level detection in tissue lysates and for localization work in fixed brain sections.