Anti-ACHE Antibody

The ACHE antibody from Antibodies.com is a rabbit polyclonal IgG reagent raised against acetylcholinesterase, the enzyme that terminates cholinergic signaling by hydrolyzing acetylcholine at synaptic and neuromuscular junctions. Provided as a 100 µl unconjugated aliquot, this Primary Antibodies reagent is validated for Western blot, immunohistochemistry, immunofluorescence, and flow cytometry on human and mouse samples.

Researchers in neuroscience and toxicology use this antibody to map cholinergic neuron populations, monitor AChE expression in neurodegenerative disease models including Alzheimer's disease, and study the impact of organophosphate exposure or anticholinergic therapeutics on tissue. The polyclonal format increases the likelihood of detecting multiple epitopes on the enzyme, useful for tracking processed or isoform-specific variants in cell culture and in vivo studies.

Storage and handling: aliquot upon receipt and store at -20 degrees C; avoid repeated freeze-thaw cycles to preserve antibody activity. The unconjugated format also provides flexibility for custom labeling with fluorophores, biotin, or enzymes depending on downstream assay needs.