Anti-ACAA1 Antibody

Produced by Antibodies.com as a rabbit polyclonal reagent, this unconjugated antibody recognizes Acetyl-CoA Acyltransferase 1 (ACAA1), a peroxisomal thiolase enzyme that catalyzes the terminal step of peroxisomal fatty acid beta-oxidation by cleaving 3-ketoacyl-CoA into acetyl-CoA and a shortened acyl-CoA chain. ACAA1 plays a central role in straight-chain and branched-chain lipid catabolism, and changes in its expression or activity have been linked to metabolic disorders and peroxisomal biogenesis defects. The reagent is formulated at 1 mg/ml in PBS with 0.1% sodium azide as a preservative and 50% glycerol as a cryoprotectant, and is provided as a 100 µl aliquot. It is validated for Western blot (WB) and immunohistochemistry (IHC) applications, with verified reactivity against human, mouse, and rat samples, supporting translational studies that compare protein expression across species and tissue types. Researchers investigating peroxisomal beta-oxidation, very-long-chain fatty acid metabolism, hepatic lipid handling, and related metabolic disease mechanisms can use this reagent for both tissue-section localization and lysate-based detection workflows.