Anti-ABLIM1 Antibody

ABLIM1 (Actin-Binding LIM Protein 1) is a cytoskeletal scaffold protein featuring an N-terminal actin-binding domain followed by four tandem LIM zinc-finger domains. It cross-links actin filaments and participates in axon guidance, retinal development, and cytoskeletal remodeling in differentiated neurons and epithelia.

This rabbit polyclonal reagent from Antibodies.com targets ABLIM1 and is validated for Western Blot and Immunohistochemistry on Human and Mouse samples. Provided as 100 µl of unconjugated antisera, the antibody pairs well with HRP- or fluorophore-conjugated secondary antibodies for flexible detection workflows. Polyclonal reactivity across multiple epitopes of ABLIM1 yields robust signal in IHC on formalin-fixed tissue sections and clear bands in WB of cell lysate and tissue homogenate preparations.

ABLIM1 expression has been investigated in studies of retinal ganglion cell differentiation, neuronal pathfinding, and cytoskeletal regulation in cancer cell lines, where altered LIM-domain scaffolding activity influences motility and adhesion. The unconjugated format lets researchers select their own label and detection chemistry, including chromogenic DAB staining or fluorescent multiplexing in immunofluorescence protocols. Store refrigerated and minimize freeze-thaw cycles to preserve antibody activity across repeated experiments. Suitable for cytoskeleton, neuroscience, and ophthalmology research investigating ABLIM1 function in cytoskeletal organization and developmental signaling contexts.