Anti-ABL1 (L406) Antibody

Raised in rabbit, this unconjugated polyclonal reagent from Antibodies.com binds the L406 epitope region of ABL1, a non-receptor tyrosine kinase implicated in cell cycle regulation, cytoskeletal dynamics, and the DNA damage response. The 50 µl aliquot is supplied at 1 mg/ml in phosphate buffered saline (PBS) containing 0.05% sodium azide at approximately pH 7.2, and is validated for western blot (WB) and immunohistochemistry (IHC) on human, mouse, and rat samples. Endogenous total ABL1 protein can be visualized in lysates and fixed tissue sections, supporting studies of normal kinase signaling and the BCR-ABL fusion that drives chronic myeloid leukemia. The reagent serves as a research use only tool for work in oncogenesis, signal transduction, and leukemia mechanisms, with the polyclonal format offering broader epitope coverage than a monoclonal reagent.