Anti-Abl1 Antibody

From Antibodies.com, this unconjugated rabbit polyclonal antibody targets Abl1 (c-Abl), a non-receptor tyrosine kinase involved in cytoskeletal regulation, DNA damage response, and downstream signal transduction. The reagent is validated for Western blot and ELISA workflows and reacts with human, mouse, rat, and monkey samples, supporting comparative studies in oncology and cell biology where the BCR-ABL fusion and related pathways are of interest.

Supplied as 100 µl of polyclonal antiserum, the antibody is unconjugated to allow flexible pairing with secondary detection chemistries such as HRP, fluorophore, or biotin depending on assay design. Polyclonal reactivity is useful when probing Abl1 isoforms, post-translational modifications, or low-abundance targets where epitope diversity improves signal coverage. Researchers studying chronic myeloid leukemia models, tyrosine kinase signaling cascades, and substrate phosphorylation patterns can apply this reagent in standard immunoblotting protocols.

The product is provided as a single vial and should be handled and stored according to standard antibody guidance to preserve activity across multiple experiments. Its cross-species reactivity makes it a practical choice for translational work bridging rodent disease models with human clinical specimens.