Anti-ABHD6 Antibody

Raised in rabbit against the postsynaptic serine hydrolase ABHD6, this unconjugated polyclonal reagent from Antibodies.com is supplied as 100 µl and validated for Western blot and immunofluorescence detection in human, mouse, and rat samples.

ABHD6 hydrolyzes the endocannabinoid 2-arachidonoylglycerol (2-AG) at the synapse and modulates microglial activation, making it a frequent target in studies of neuroinflammation, synaptic lipid signaling, and metabolic regulation. Researchers use this antibody to map ABHD6 expression across neuronal cultures, brain tissue sections, and heterologous cell models expressing the human or rodent ortholog. The polyclonal format recognizes multiple epitopes on the ABHD6 protein, supporting reproducible detection in denatured lysates and in fixed cells.

For best results, aliquot on receipt and store refrigerated; the reagent is intended for research use only and pairs with standard rabbit-IgG secondary antibodies. Immunofluorescence workflows typically include fixation and permeabilization, while Western blot uses standard SDS-PAGE lysate preparation.