Anti-ABCG2 Antibody

The ABCG2 protein (also known as BCRP, Breast Cancer Resistance Protein) is an ATP-binding cassette transporter that acts as an efflux pump for xenobiotics and is studied in multidrug resistance research, stem cell biology, and drug disposition across the blood-brain barrier and placenta. This unconjugated rabbit polyclonal antibody from Antibodies.com targets ABCG2 and is supplied as 100 µl of reagent in a single vial. Validated applications include Western blot for detection of the ~72 kDa ABCG2 band, immunohistochemistry on fixed tissue sections, and flow cytometry for cell-surface expression analysis. The antibody reacts with human, mouse, and rat samples, supporting comparative studies across these species. IgG isotype and polyclonal clonality give flexibility in detection when paired with secondary reagents. Refrigerated storage and aliquoting to limit freeze-thaw cycles help preserve antibody activity over multiple experiments.