Anti-ABCG2 Antibody

This rabbit polyclonal IgG reagent from Antibodies.com targets the human ATP-binding cassette sub-family G member 2 (ABCG2), a half-transporter widely studied for its role in cellular efflux of xenobiotics, multidrug resistance phenotypes, and side-population stem cell biology. It is supplied as a 50 µl liquid aliquot in unconjugated format, giving researchers flexibility to pair it with HRP, fluorophore, or biotin secondary reagents depending on the chosen detection system.

Validated for Western blot detection in human samples, the antibody is commonly applied to profile transporter expression across cancer cell lines, characterize chemotherapy-resistant populations, and map ABCG2 levels in tissue lysates under reducing conditions. Its specificity for ABCG2 (also known as BCRP) makes it relevant for investigations of protective function at the blood-brain, placental, and intestinal barriers, and for studies dissecting ATP-driven drug efflux mechanisms.

For handling, aliquot the reagent upon first use and store frozen at -20 °C; avoid repeated freeze-thaw cycles to preserve binding activity, and centrifuge briefly before opening the vial. With rabbit host, polyclonal clonality, and IgG isotype, this Antibodies.com primary antibody supports immunoblotting workflows aimed at resolving ABCG2-mediated transport and resistance profiles in cell and tissue research models.