Anti-ABCC4 Antibody

Produced in rabbits and validated for Western blot (WB) and immunohistochemistry (IHC), this Anti-ABCC4 Antibody from Antibodies.com targets ABCC4, also known as MRP4 (Multidrug Resistance-associated Protein 4), a member of the ATP-binding cassette (ABC) transporter superfamily that mediates cellular efflux of organic anions, cyclic nucleotides (cAMP and cGMP), prostaglandins, and certain antiviral and anticancer drugs.

Unconjugated and polyclonal, the reagent recognizes ABCC4 in human, mouse, and rat samples, supporting cross-species studies of xenobiotic transport, multidrug resistance in cancer cells, and renal and hepatic clearance pathways. It is supplied as 100 µl of serum in a vial, a format that accommodates multiple blotting or staining runs.

Researchers commonly use this antibody to investigate drug efflux mechanisms in tumor cell lines, characterize cGMP signaling in vascular and renal tissues, and explore the role of MRP4 in inflammatory mediator release and bone metabolism. Its reactivity across three mammalian species is valuable for translational work moving between rodent models and human tissue specimens.