Anti-ABCB6 Antibody

Raised in rabbit against the ATP-binding cassette subfamily B member 6 (ABCB6) transporter, this unconjugated polyclonal reagent from Antibodies.com is supplied as 100 µl of ready-to-use serum and is validated for Western blot and immunohistochemistry workflows on human and mouse samples. ABCB6 is a mitochondrial outer-membrane protein best known for importing coproporphyrinogen III into mitochondria during heme biosynthesis, and it has additionally been implicated in cellular iron handling, plasma membrane porphyrin transport in erythrocytes and melanocytes, and loss-of-function variants underlying familial pseudohyperkalemia and dyschromatosis universalis hereditaria. Investigators studying mitochondrial transporters, porphyrin metabolism, or erythrocyte membrane biology can deploy this antibody to probe endogenous ABCB6 expression across tissues, while the unconjugated format leaves the choice of HRP, biotin, or fluorescent secondary labelling entirely with the user. Short-term storage at 4 °C is recommended, and aliquoting the 100 µl volume on first use is advised to limit freeze-thaw cycles and preserve lot-to-lot performance.