Anti-ABCB1 Antibody

Raised in rabbit hosts, this unconjugated polyclonal IgG antibody targets the human, mouse, and rat ABCB1 transporter, commonly known as P-glycoprotein (P-gp) or MDR1, a 170 kDa ATP-binding cassette efflux pump implicated in multidrug resistance and xenobiotic disposition across the blood-brain barrier, intestinal epithelium, and hepatic tissue. The 50 µl reagent from Antibodies.com is validated for Western blot and immunofluorescence workflows, offering researchers a flexible tool for studying drug transport biology, chemotherapy resistance mechanisms, and the tissue-specific expression patterns that govern pharmacokinetics. Its polyclonal nature allows recognition of multiple epitopes on the target protein, which can improve signal robustness in detection assays compared with monoclonal alternatives.